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In patients with cyanotic congenital heart disease (CCHD), the need for antibiotic prophylaxis for infective endocarditis is well known among dentists, but not many dentists are aware of the associated hemorrhagic tendencies in such patients. We report a case of post-extraction hemorrhage in a patient with Eisenmenger's syndrome and discuss the importance of more elaborate hematologic evaluation in patients with CCHD before oral surgery.